The number of infections with the fungus Candida auris is also increasing in Germany. This is shown in a new study by research teams from Würzburg, Jena and Berlin. Despite low numbers, scientists advise precautionary measures.
Immunoglobulin G antibodies (IgB) play an important role as drivers of inflammation in infectious diseases and autoimmune diseases. However, if the same immunoglobulin antibodies from the blood plasma of healthy donors are cleansed and injected into a patient’s bloodstream, they exhibit anti-inflammatory effects and have a positive effect on the immune system. The cause of this was unknown to a large extent up to now.
A vitamin D3 deficiency can lead to severe symptoms, for example in people suffering from allergic asthma. This has already been shown in several studies. However, we still do not fully understand how exactly this vitamin influences the cellular inflammatory reaction in the body.
HTLV-1 triggers aggressive forms of leukemia or an incurable spinal cord disease that leads to paralysis: the virus is the often ignored but no less insidious sibling of the HIV virus that causes AIDS and also belongs to the family of retroviruses. A group of researchers from TU Dresden, the company PROVIREX Genome Editing Therapies and Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) have now provided initial proof of concept for a potential therapeutic approach.
Intestinal bacteria are often the trigger of complications after surgery. This is shown in a new study by research teams from Inselspital (University Hospital Bern), the University of Bern and the University of Würzburg. A solution to this problem could come from the liver.
When you hear the word microbiome, the chances are you will think of the gut. But the microbiome is so much more, namely the total of all microorganisms living on and in the human body. Skin, lungs or the digestive system, the mouth, throat, nose or the genital tract: they are all home to tiny living organisms such as bacteria, viruses or fungi. When the balance is correct, they are beneficial to human health. But what does the ideal microbiome look like? And what influence do quintillions of invisible organisms have on human health and disease?
Universitätsklinikum Erlangen is the first in the world to use CAR T-cells to successfully treat a patient suffering from a severe case of muscle inflammation (myositis). The disease is triggered by a malfunction in the immune system that leads to inflammation of the muscles, and the risk of developing a very severe form of the disease is high. The journal Lancet has now published news of the successful treatment in a case report.
A team of researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen has gained new insights into the maturation of SARS-CoV-specific antibodies after multiple vaccinations with the mRNA vaccine Comirnaty. They have now published their work in the journal Science Immunology.
A newly developed rapid test needs only a few seconds to reliably detect pathogens such as SARS-CoV-2. It is based on specially designed magnetic nanoparticles.
How do the gut and the brain interact, and can this even trigger disease? There is growing consensus within the research community that the nervous and digestive systems interact with each other. How exactly, however, is still largely unknown. The German Research Foundation (DFG) is now funding a new clinical research unit at Friedrich-Alexander-Universität Erangen-Nürnberg (FAU) that will investigate the interaction between the digestive and nervous systems with reference to inflammatory and degenerative diseases, the first collaborative research group in Germany to explore the “gut-brain axis”.
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