Certain immune cells can cause damage to the aging central nervous system, according to a novel study by scientists of the University Hospital and the University of Würzburg.
Researching the effects of plastic particles on the human body and developing a health policy strategy for assessing the resulting risks is the goal of the new European research network PlasticsFatE. The University of Bayreuth, together with 26 other universities, institutes, and organisations from ten EU member states, is participating in the project. The European Union is funding the four-year project to the tune of € 6 million, with the University of Bayreuth receiving more than € 465,000. The project was launched on 28 April 2021 at a virtual kick-off event for its partners.
Genetically engineered animals provide important insights into the molecular basis of health and disease. Research has focused mainly on genetically modified mice, although other species, such as pigs, are more similar to human physiology. Researchers at the Technical University of Munich (TUM) have now generated chickens and pigs in which target genes in desired organs can be efficiently altered.
The plasticisers contained in many everyday objects can impair important brain functions in humans. Biologists from the University of Bayreuth warn of this danger in an article in "Communications Biology". Their study shows that even small amounts of the plasticisers bisphenol A and bisphenol S disrupt the transmission of signals between nerve cells in the brains of fish. The researchers consider it very likely that similar interference can also occur in the brains of adult humans. They therefore call for the rapid development of alternative plasticisers that do not pose a risk to the central nervous system.
Around two thirds of men and half of women in Germany* are overweight, according to statistics collected by the German Obesity Society. Concurrently millions of people want to lose weight. One way to do this is exercising. But what influence does sport have on (direct) eating habits? Scientists at the Technical University of Munich (TUM) and the University of Nebraska (USA) have now investigated this question for the first time.
An international team of researchers led by Prof.Dr Katharina Zimmermann has discovered that the cold thermoreceptor TRPC5 causes sensitivity to cold temperatures in teeth. The researchers have published their findings in the renowned scientific journal ‘Science Advances’. ‘Toothache is a nightmare for many people and sensitive teeth can be just as painful,’ says Prof. Dr. Katharina Zimmermann from the Department of Anaesthesiology at Universitätsklinikum Erlangen. ‘People with over-sensitive teeth are all too familiar with the painful sensation they experience as soon as they start eating ice cream.’
Regulatory T cells (Treg cells) are an immune cell type that reduces excessive immune responses and protects the body against autoimmune diseases. This study shows that Treg cells in human tissues acquire tissue-regenerative features and describes a method to generate these cells in the laboratory.
New tool for cell biology: Würzburg researchers have developed a light sensor with an enzyme function that can be switched on and off with different light colours.
Scientists at the University of Würzburg together with a pharmaceutical company are working on a novel approach to oral vaccination against the coronavirus.
Capturing the structure of large molecular complexes with variable shape is an extremely difficult task. Scientists from Würzburg and Montpellier now have been able to do it – thanks to a new approach regarding an important protein machine.