Researchers at the University of Bayreuth have, for the first time, deciphered key steps in the biosynthetic mechanism of the potential anti-cancer agent fostriecin. The team led by Prof. Dr. Frank Hahn has succeeded in producing all enzymes involved in the process in the laboratory and examining them individually under controlled conditions. In the long term, the findings may pave the way for more efficient production of the compound and open up new avenues in cancer therapy. The researchers have reported their findings in the renowned journal Nature Communications.
• 60-fold greater efficacy than standard medication • Results achieved in laboratory and animal studies • 43 percent of the global population infected with H. pylori A significant step toward the potential prevention of stomach cancer: Researchers at the Technical University of Munich (TUM) have increased the effectiveness of a standard antibiotic by a factor of 60 through targeted chemical modifications. In laboratory and animal studies, the new drug candidate successfully combats the bacterium Helicobacter pylori, which is closely associated with the development of stomach cancer. The study findings were published in the journal Nature Microbiology.
A lack of vitamin B2 makes tumour cells more susceptible to a unique form of cell death. This was discovered by researchers at the Rudolf Virchow Centre at the University of Würzburg.
