In the cultivation of organic cacao, many factors determine the yield. An international research team with scientists from the universities of Würzburgh and Göttingen has now identified important players and their combined effects.
Researchers at the Rudolf Virchow Center of the University of Würzburg have unveiled the crystal structures of UBA6 in complex with either ATP or the ubiquitin-like protein FAT10. These results provide the foundation to study the individual roles of UBA6 towards the attachment of either ubiquitin or FAT10 to target proteins and the downstream cellular pathways with possible implications for the etiology of certain tumors. This study was published in the journal Nature Communications.
Lymph nodes trigger very different immune responses – depending on which body tissue they are connected to. Special T cells are responsible for this newly discovered relation.
Completely unexpectedly, the enzyme ceramidase emerges as a new target structure for the therapy of SARS-CoV-2 infections. This is reported by Würzburg researchers in "Cells".
The Free State of Bavaria is funding a new research project on quantum sensors with three million euros. Among other things, it aims to further improve molecular and medical imaging.
Researchers at the University of Würzburg develop the "photoswitching fingerprint analysis". A unique technology that for the first time allows the analysis of molecular processes and the regulation of individual proteins in living cells with sub-10 nm spatial resolution. The application ranges from biological to medical research and has been published in the renowned journal Nature Methods.
Poxviruses pose a threat to humanity that should be taken seriously, as the current outbreak of monkeypox shows. A research team from the University of Würzburg is now working on the development of new drugs.
Neutrinos that reach our planet from the depths of the Universe originate from blazars. Astrophysicists have proven this for the first time.
Some lung tumours do not respond to radiation therapy. This effect can be reversed by blocking an enzyme in the tumour cells, as Würzburg researchers report.
Similar to the vaccines against the coronavirus, RNA-based antibiotics could significantly improve modern medicine. Research teams from Würzburg have investigated the prerequisites that such antibiotics must meet for this strategy to work.
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