Proteins control and organize almost every aspect of life. The totality of all proteins in a living organism, a tissue or a cell is called the proteome. Using mass spectrometry, researchers at the Technical University of Munich (TUM) characterize the proteome, or protein complement of the genome, in important model organisms. In 2014, a team at the Chair of Proteomics and Bioanalytics reported a draft human proteome for the first time, followed by that of the model plant Arabidopsis thaliana in 2020, and now that of the most common laboratory mouse.
After 60 years of unsuccessful searches, an international research team has discovered a neutral nucleus for the first time – the tetra-neutron. The collaboration succeeded in creating an isolated four-neutron system with low relative kinetic energy in a volume equivalent to an atomic nucleus. The researchers overcame the experimental challenge by using a new method: a radioactive neutron-rich ⁸He beam and a fast high-energy reaction with a proton
Researchers have developed 3D printed artificial heart valves designed to allow a patient’s own cells to form new tissue. To form these scaffolds using melt electrowriting – an advanced additive manufacturing technique – the team has created a new fabrication platform that enables them to combine different precise, customized patterns and hence to fine-tune the scaffold’s mechanical properties. Their long-term goal is to create implants for children that develop into new tissue and therefore last a lifetime.
Researchers at the Technical University of Munich (TUM) have developed a film that not only protects wounds similar to the way a bandage does, but also helps wounds to heal faster, repels bacteria, dampens inflammation, releases active pharmaceutical ingredients in a targeted manner and ultimately dissolves by itself. This is all made possible by its dedicated design and the use of mucins, molecules which occur naturally in mucous membranes.
Machine learning is playing an ever-increasing role in biomedical research. Scientists at the Technical University of Munich (TUM) have now developed a new method of using molecular data to extract subtypes of illnesses. In the future, this method can help to support the study of larger patient groups.
Scientists at the Technical University of Munich (TUM) conducted a multi-year empirical study to assess the impact of trees on city temperatures. Taking the city of Würzburg as an example, the researchers showed that vegetation cover of approximately 40 percent is needed to bring about lower summer temperatures.
Following a heart attack, the human body is incapable of repairing lost tissue due to the heart’s inability to generate new muscle. However, treatment with heart progenitor cells could result in the formation of functional heart cells at injured sites. This new therapeutic approach is introduced by an international team in Nature Cell Biology. The aim is to start clinical studies within the next two years.
A low-cost and easy-to-manufacture lighting technology can be made with light-emitting electrochemical cells. Such cells are thin-film electronic and ionic devices that generate light after a low voltage is applied. Researchers at the Technical University of Munich (TUM) and the University of Turin have now used extensive data analysis to create first-class electrochemical cells from copper complexes that emit blue and white light.
Production workers instructed with augmented reality glasses can work much faster than colleagues instructed with analog methods. However, an international study shows that they are less capable of internalizing their tasks and of making suggestions to improve production processes. These insights may help companies when adapting AR applications to their needs and balancing productivity gains against process optimization priorities.
Conventional vaccination campaign messages often miss their targets. A study in eight European countries shows that information on the benefits of vaccines can even reduce the willingness to get immunized. The researchers also looked into the factors that influenced the impact of messages, including low health literacy. A further study provides indications of the relationship between trust in vaccines and their approval procedures.
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