Parasitic worms help Professor Clarissa Prazeres da Costa and her team better understand the human immune system in order to find solutions to global health problems.
Why do blood clots develop in the first place—and why do they tend to recur? LMU researcher Konstantin Stark believes that the answers lie in the immune system.
At RCI, the Regensburg Center for Interventional Immunology, international research groups develop immunotherapies and cellular therapies in order to help treating patients suffering from tumors, chronic inflammation or autoimmunity.
From junior research group leader to full professor and spokesperson of the Research Center for Infectious Diseases (ZINF) at the University of Würzburg. This is the scientific career path of Cynthia Sharma.
Disruptions of mitochondrial functions have a fundamental influence on Crohn’s disease. This connection has now been demonstrated by researchers at the Technical University of Munich (TUM). They showed that defective mitochondria in mice trigger symptoms of chronic intestinal inflammation and influence the microbiome.
An international research team led by Prof. Dr. Janosch Hennig from the University of Bayreuth has discovered how the TRIM25 protein contributes to defense against RNA viruses whose genetic material is contained as ribonucleic acid (RNA). The results provide a better understanding of the molecular mechanisms of the human immune system. The researchers have now reported their findings in Nature Communications.
Reinforcement for the Max Planck Research Group of Systems Immunology in Würzburg: ERC Starting Grant winner Dr Jakob Zimmermann is launching his team here.
Chlamydiae are sexually transmitted pathogens that can apparently survive in the human gut for a long time. Researchers from Würzburg and Berlin report this in the journal PLOS Pathogens.
Optimizing CAR-T Cells with CRISPR 2.0 As part of the German Research Foundation (DFG) Emmy Noether Program, Dr. Karl Petri is establishing a research group at the University Hospital Würzburg (UKW) to develop and enhance novel CRISPR 2.0 tools for generating and improving cancer-targeted CAR-T cell products.
Biogeography researchers at the University of Bayreuth have developed the first model that simulates the spatial and temporal risk of West Nile virus infection in resident birds, migratory birds and humans in Germany. In doing so, they are laying the foundations for a warning system for diseases whose transmission is influenced by climate change.